Publication List
Year 2024
Subramanian K, Varghese R, Pochedly M, Muralidaran V, Yazigi N, Kaufman S, Khan K, Vitola B, Kroemer A, Fishbein T, Ressom H, Ekong UD. Non-fatal outcomes of COVID-19 disease in pediatric organ transplantation associates with down-regulation of senescence pathways. Sci Rep. 2024 Jan 22;14(1):1877. PMID: 38253675
Year 2023
Yichen Guo, Marie Denis, Rency S. Varghese, Sidharth S. Jain, Ma. Bayesian Approach Integrating Prior Knowledge for Identifying miRNA-mRNA Interactions in Hepatocellular Carcinoma. IEEE International Conference on Bioinformatics and Biomedicine (BIBM- 2023).Year: 2023, Pages: 3768-3774; 10.1109/BIBM58861.2023.10385314.
Rashid MM, Varghese RS, Ding Y, Ressom HW. Biomarker Discovery for Hepatocellular Carcinoma in Patients with Liver Cirrhosis Using Untargeted Metabolomics and Lipidomics Studies. Metabolites. 2023 Oct 2;13(10):1047. doi:10.3390/metabo13101047. PMID: 37887372
Chau HYK, Ao H, Zhang X, Gao S, Varghese RS, Ressom HW (2023). Deep Learning Based Metabolite Annotation. Annu Int Conf IEEE Eng Med Biol Soc. 2023 Jul;2023:1-4. doi: 10.1109/EMBC40787.2023.10341007.PMID: 3808295
Jain SS, McNamara ME, Varghese RS, Ressom HW. Deconvolution of immune cell composition and biological age of hepatocellular carcinoma using DNA methylation. Methods. 2023 Oct;218:125-132. doi: 10.1016/j.ymeth.2023.08.004. Epub 2023 Aug 11. PMID: 37574160
Salman Sajid M, Saleem S, Jabeen F, Waqas Ishaq M, Najam-Ul-Haq M, Ressom HW. Mapping the low abundant plasma glycoproteome using Ranachrome-5 immobilized magnetic terpolymer as improved HILIC sorbent. J Chromatogr B Analyt Technol Biomed Life Sci. 2023 Jul 1;1227:123846. doi: 10.1016/j.jchromb.2023.123846. Epub 2023 Aug 4. PMID: 37567067
Max Stevenson, Rency Varghese, Michaeline L Hebron, Xiaoguang Liu, Nick Ratliff, Amelia Smith, R Scott Turner, Charbel Moussa. Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer’s disease. J Neuroinflammation. 2023 May 16;20(1):116. doi: 10.1186/s12974-023-02802-0. PMID: 37194065
Li J, Greytak SR, Guan P, Engel KB, Goerlitz DS, Islam M, Varghese RS, Moore HM, Ressom HW. Formalin Fixation, Delay to Fixation, and Time in Fixative Adversely Impact Copy Number Variation Analysis by aCGH. Biopreserv Biobank. 2023 Aug;21(4):407-416. doi: 10.1089/bio.2022.0036. Epub 2022 Sep 27. PMID: 36169416
Suryakant Niture, Sashi Gadi, Qi Qi, Maxwell Afari Gyamfi, Rency S Varghese, Leslimar Rios-Colon, Uchechukwu Chimeh, Habtom W Ressom, Deepak Kumar. MicroRNA-483-5p Inhibits Hepatocellular Carcinoma Cell Proliferation, Cell Steatosis, and Fibrosis by Targeting PPARα and TIMP2. 2023, Cancers 15 (6), 1715. PMID: 36980601
Year 2022
Sajid MS, Saleem MN, Jabeen F, Saleem S, Iqbal S, Habib S, Ashiq MN, Ressom HW, Najam-Ul-Haq M. Human serum N-glycome profiling via the newly developed asparagine immobilized cellulose/polymer nanohybrid. J Sep Sci. 2022 Dec;45(23):4236-4244. doi: 10.1002/jssc.202200179. Epub 2022 Nov 3. PMID: 36168850
Karen E Anderson, Max Stevenson, Rency Varghese, Michaeline L Hebron, Erin Koppel, Mara McCartin, Robin Kuprewicz, Sara Matar, Dalila Ferrante, Charbel Moussa. Alteration of Autophagy and Glial Activity in Nilotinib-Treated Huntington’s Disease Patients. 2022, Metabolites 12 (12), 1225
Jain SS, Barefoot ME, Varghese RS, Ressom HW. Cell-type Deconvolution and Age Estimation Using DNA Methylation Reveals NK Cell Deficiency in the Hepatocellular Carcinoma Microenvironment. Proceedings (IEEE Int Conf Bioinformatics Biomed). 2022 Dec;2022:444-449. doi:10.1109/BIBM55620.2022.9995041. PMID: 37663782
Marie Denis, Rency S Varghese, Megan E Barefoot, Mahlet G Tadesse, Habtom W Ressom.A Bayesian two-step integrative procedure incorporating prior knowledge for the identification of miRNA-mRNAs involved in hepatocellular carcinoma. 2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 81-86
Shijinqiu Gao, Hoi Yan Katharine Chau, Kuijun Wang, Hongyu Ao, Rency S Varghese, Habtom W Ressom. Convolutional Neural Network-Based Compound Fingerprint Prediction for Metabolite Annotation. 2022, Metabolites 12 (7), 605
Sajid MS, Saleem S, Jabeen F, Najam-Ul-Haq M, Ressom HW. Terpolymeric platform with enhanced hydrophilicity via cysteic acid for serum intact glycopeptide analysis. Mikrochim Acta. 2022 Jul 13;189(8):277. doi:10.1007/s00604-022-05343-0. PMID: 35829791
Patricia A Da Cunha, Diana Nitusca, Luisa Matos Do Canto, Rency S Varghese, Habtom W Ressom, Shawna Willey, Catalin Marian, Bassem R Haddad. Metabolomic Analysis of Plasma from Breast Cancer Patients Using Ultra-High-Performance Liquid Chromatography Coupled with Mass Spectrometry: An Untargeted Study. PMID: 35629952 PMCID: PMC9147455 DOI: 10.3390/metabo12050447
Year 2021
Sajid MS, Saleem S, Jabeen F, Fatima B, Zulfikar M, Ashiq MN, Ressom HW, Pukala TL, Najam-Ul-Haq M. Iminodiacetic acid (IDA)-generated mesoporous nanopolymer: a template to relate surface area, hydrophilicity, and glycopeptides enrichment. Mikrochim Acta. 2021 Nov 11;188(12):417. doi: 10.1007/s00604-021-05074-8. PMID: 34762162
Varghese RS, Barefoot ME, Jain S, Chen Y, Zhang Y, Alley A, Kroemer AK, Tadesse MG, Kumar D, Sherif ZA, Ressom HW (2021). Integrative analysis of DNA methylation and microRNA expression reveals mechanisms of racial heterogeneity in hepatocellular carcinoma. Front. Genet. 10.3389/fgene.2021.708326
Kang J, Loh K, Belyayev L, Cha P, Sadat M, Khan K, Gusev Y, Bhuvaneshwar K, Ressom H, Moturi S, Kaiser J, Hawksworth J, Robson SC, Matsumoto CS, Zasloff M, Fishbein TM, Kroemer A (2021). Type 3 innate lymphoid cells are associated with a successful intestinal transplant. Am J Transplant. 21(2):787-797. doi: 10.1111/ajt.16163. PMID: 32594614
Fowler AJ, Ahn J, Hebron M, Chiu T, Ayoub R, Mulki S, Ressom H, Torres-Yaghi Y, Wilmarth B, Pagan FL, Moussa C. CSF MicroRNAs Reveal Impairment of Angiogenesis and Autophagy in Parkinson Disease. Neurol Genet. 2021 Nov 12;7(6):e633. doi: 10.1212/NXG.0000000000000633. PMID: 34786477
Year 2020
Fowler AJ, Hebron M, Balaraman K, Shi W, Missner AA, Greenzaid JD, Chiu TL, Ullman C, Weatherdon E, Duka V, Torres-Yaghi Y, Pagan FL, Liu X, Ressom H, Ahn J, Wolf C, Moussa C (2020). Discoidin Domain Receptor 1 is a therapeutic target for neurodegenerative diseases. Hum Mol Genet. 29(17):2882-2898. doi: 10.1093/hmg/ddaa177. PMID: 32776088
Fan Z, Alley A, Ghaffari, Ressom HW (2020). MetFID: Artificial neural network-based compound fingerprint prediction for metabolite annotation. Metabolomics 16(10):104. PMID: 32997169
Fan Z, Zhou Y, Ressom HW (2020). MOTA: Network-based multi-omic data integration for biomarker discovery. Metabolites 10(4):E144. doi:10.3390/metabo10040144. PMID: 32276350
Varghese RS, Zhou Y, Barefoot M, Chen Y, Di Poto C, Balla AK, Oliver E, Sherif ZA, Kumar D, Kroemer AH, Tadesse MG, Ressom HW (2020). Identification of miRNA-mRNA associations in hepatocellular carcinoma using hierarchical integrative model. BMC Med Genomics. 13(1):56. doi: 10.1186/s12920-020-0706-1. PMID: 32228601
Varghese RS, Zhou Y, Chen Y, Barefoot ME, Tadesse MG, Ressom HW (2020). Epigenetic changes associated with mechanisms of disparities in hepatocellular carcinoma. Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:5320-5325. doi: 10.1109/EMBC44109.2020.9176036. PMID: 33019185
Chen Y, Barefoot ME, Varghese R, Wang K, Di Poto C, Ressom HW (2020). Integrative Analysis to Identify Race-Associated Metabolite Biomarkers for Hepatocellular Carcinoma. Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:5300-5303. doi: 10.1109/EMBC44109.2020.9175697. PMID: 33019180
Fowler AJ, Hebron M, Balaraman K, Shi W, Missner AA, Greenzaid JD, Chiu TL, Ullman C, Weatherdon E, Duka V, Torres-Yaghi Y, Pagan FL, Liu X, Ressom H, Ahn J, Wolf C, Moussa C (2020). Discoidin Domain Receptor 1 is a therapeutic target for neurodegenerative diseases. Hum Mol Genet. ddaa177. doi: 10.1093/hmg/ddaa177. PMID: 32776088
Kang J, Loh K, Belyayev L, Cha P, Sadat M, Khan K, Gusev Y, Bhuvaneshwar K, Ressom H, Moturi S, Kaiser J, Hawksworth J, Robson SC, Matsumoto CS, Zasloff M, Fishbein TM, Kroemer A (2020).Type 3 innate lymphoid cells are associated with a successful intestinal transplant. Am J Transplant. doi: 10.1111/ajt.16163. PMID: 32594614
Fu Y, Tsai T-H, Mao C, Mun SK, Ressom HW, Wang M, Zhang Z, Wang Y. (2020). Biological Computing. In: Biomedical Information Technology, pp. 81-104. ISBN: 9780128160343; DOI: 10.1016/B978-0-12-816034-3.00003-1 (https://www.sciencedirect.com/science/article/pii/B9780128160343000031)
Year 2019
Yao Z, Di Poto C, Mavodza G, Oliver E, Ressom HW, Sherif ZA (2019). DNA methylation activates TP73 expression in hepatocellular carcinoma and gastrointestinal cancer. Scientific Reports 2019 Dec 18;9(1):19367. PMID: 31852961
Barefoot ME, Chen Y, Varghese RS, Zhou Y, and Ressom HW (2019). Integrative analysis of DNA methylation and gene expression patterns in tissues from hepatocellular carcinoma patients. Proceedings of the IEEE International Conference on Bioinformatics and Biomedicine (BIBM), San Diego, CA, Nov. 18-21, 2019, pp. 267-274.
Fan Z, Ghaffari K, Alley A, Ressom HW (2019). Metabolite identification using artificial neural network. Proceedings of the IEEE International Conference on Bioinformatics and Biomedicine (BIBM), San Diego, CA, Nov. 18-21, 2019, pp. 244-248.
Barefoot ME, Varghese RS, Zhou Y, Di Poto C, Ferrarini A, Ressom HW (2019). Multi-omic pathway and network analysis to identify biomarkers for hepatocellular carcinoma. Conf Proc IEEE Eng Med Biol Soc. 2019 Jul;2019:1350-1354. doi: 10.1109/EMBC.2019.8856576. PMID: 31946143
Fan, Z, Zhou Y, Ressom HW (2019). MOTA: Multi-omic integrative analysis for biomarker discovery. Conf Proc IEEE Eng Med Biol Soc. 2019 Jul;2019:243-247. doi: 10.1109/EMBC.2019.8857049. PMID: 31945887
Su S, Di Poto C, Kroemer AH, Cui W, Roy R, Liu X, Ressom HW (2019). Establishment of ornithine transcarbamylase deficiency-derived primary human hepatocyte with hepatic functions. Exp Cell Res. 2019 Nov 1;384(1):111621. doi: 10.1016/j.yexcr.2019.111621. Epub 2019 Sep 9. PMID: 31513782
Thangarajh M, Zhang A, Gill K, Ressom HW, Li Z, Varghese RS, Hoffman EP, Nagaraju K, Hathout Y, Boca SM (2019). Discovery of potential urine-accessible metabolite biomarkers associated with muscle disease and corticosteroid response in the mdx mouse model for Duchenne. PLoS One. 2019 Jul 16;14(7):e0219507. doi: 10.1371/journal.pone.0219507. eCollection 2019. PMID: 31310630
Ferrarini A, Di Poto C, He S, Tu C, Varghese RS, Kara Balla A, Jayatilake M, Li Z, Ghaffari K, Fan Z, Sherif ZA, Kumar D, Kroemer A, Tadesse MG, Ressom HW (2019). Metabolomic Analysis of liver tissues for characterization of hepatocellular carcinoma. J Proteome Res. 2019 Aug 2;18(8):3067-3076. doi: 10.1021/acs.jproteome.9b00185. Epub 2019 Jul 1. PMID: 31188000
Su S, Di Poto C, Roy R, Liu X, Cui W, Kroemer A, Ressom HW (2019). Highlight article: Long-term culture and characterization of patient-derived primary hepatocytes using conditional reprogramming. Exp Biol Med (Maywood). 2019 Aug;244(11):857-864. doi: 10.1177/1535370219855398. Epub 2019 Jun 11. PMID: 31184925
White SM, Avantaggiati ML, Nemazanyy I, Di Poto C, Yang Y, Pende M, Gibney GT, Ressom HW, Field J, Atkins MB, Yi C (2019). YAP/TAZ inhibition induces metabolic and signaling rewiring resulting in targetable vulnerabilities in NF2-deficient tumor cells. Dev Cell. 2019 May 6;49(3):425-443.e9. doi: 10.1016/j.devcel.2019.04.014. PMID: 31063758
Tricoli L, Niture S, Chimeh U, Ressom H, Kumar D (2019). Role of microRNAs in the development of hepatocellular carcinoma and drug resistance. Front Biosci (Landmark Ed). 24:382-391. Review. PMID: 30468662
Year 2018
Li Z, Zuo Y, Xu C, Varghese RS, Ressom HW (2018). INDEED: R package for network based differential expression analysis. Proceedings (IEEE Int Conf Bioinformatics Biomed). 2018 Dec;2018:2709-2712. doi: 10.1109/BIBM.2018.8621426. Epub 2019 Jan 24. PMID: 31179159
Fernandez HR, Gadre SM, Tan M, Graham GT, Mosaoa R, Ongkeko MS, Kim KA, Riggins RB, Parasido E, Petrini I, Pacini S, Cheema A, Varghese R, Ressom HW, Zhang Y, Albanese C, Uren A, Paige M, Giaccone G, Avantaggiati ML (2018). The mitochondrial citrate carrier, SLC25A1, drives stemness and therapy resistance in non-small cell lung cancer. Cell Death Differ. 25(7):1239-1258. PMID: 29651165
Di Poto C, He S, Varghese RS, Zhao Y, Ferrarini A, Su S, Karabala A, Redi M, Mamo H, Rangnekar AS, Fishbein TM, Kroemer AH, Tadesse MG, Roy R, Sherif ZA, Kumar D, Ressom HW (2018). Identification of race-associated metabolite biomarkers for hepatocellular carcinoma in patients with liver cirrhosis and hepatitis C virus infection. PLoS One 13(3):e0192748. PMID: 29538406
Niture S, Gyamfi M, Kedir H, Arthur E, Ressom H, Deep G, Kumar D. Serotonin induced hepatic steatosis is associated with modulation of autophagy and Notch signaling pathway. Cell Communication and Signaling.2018 Nov 8;16(1):78. doi: 10.1186/s12964-018-0282-6. PMID: 30409162
Year 2017
Misiak MM, Hipolito MS, Ressom HW, Obisesan TO, Manaye KF, Nwulia EA. Apo E4 Alleles and Impaired Olfaction as Predictors of Alzheimer's Disease. Clin Exp Psychol. 2017;3(4). pii: 169. doi: 10.4172/2471-2701.1000169. Epub 2017 Oct 19. PMID: 29423459
Zuo Y, Cui Y, Yu G, Li R, Ressom HW* (2017). Incorporating prior biological knowledge for network-based differential gene expression analysis using differentially weighted graphical LASSO. BMC Bioinformatics. 2017 Feb 10;18(1):99. PMID: 28187708
Varghese RS, Zuo Y, Zhao Y, Zhang YW, Jablonski SA, Pierobon M, Petricoin EF, Ressom HW*, Weiner LM* (2017). Protein network construction using reverse phase protein array data. Methods 124:89-99. PMID: 28651964
Di Poto C, Ferrarini A, Zhao Y, Varghese RS, Tu C, Zuo Y, Wang M, Nezami Ranjbar MR, Luo Y, Zhang C, Desai CS, Shetty K, Tadesse MG, Ressom HW* (2017). Metabolomic characterization of hepatocellular carcinoma in patients with liver cirrhosis for biomarker discovery. Cancer Epidemiol Biomarkers Prev. 26(5):675-683. PMID: 27913395
Azizan KA, Ressom HW, Mendoza ER, Baharum SN (2017). 13C based proteinogenic amino acid (PAA) and metabolic flux ratio analysis of Lactococcus lactis reveals changes in pentose phosphate (PP) pathway in response to agitation and temperature related stresses. PeerJ. 2017 Jul 5;5:e3451. doi: 10.7717/peerj.3451. eCollection 2017. PMID: 28695065
Hsu PC, Lan RS, Brasky TM, Marian C, Cheema AK, Ressom HW, Loffredo CA, Pickworth WB, Shields PG (2017). Metabolomic profiles of current cigarette smokers. Mol Carcinog. 2017 Feb;56(2):594-606. doi: 10.1002/MID: 27341184
Hsu PC, Lan RS, Brasky TM, Marian C, Cheema AK, Ressom HW, Loffredo CA, Pickworth WB, Shields PG (2017). Menthol Smokers: Metabolomic profiling and smoking behavior. Cancer Epidemiol Biomarkers Prev. 2017 Jan;26(1):51-60. doi: 10.1158/1055-9965.EPI-16-0124. PMID: 27628308
Day TF, Mewani RR, Starr J, Li X, Chakravarty D, Ressom H, Zou X, Eidelman O, Pollard HB, Srivastava M, Kasid UN*. Transcriptome and proteome analyses of TNFAIP8 knockdown cancer cells reveal new insights into molecular determinants of cell survival and tumor progression. Methods Mol Biol. 2017;1513:83-100. PMID: 27807832
Year 2016
Wang M, Di Poto C, Ferrarini A, Yu G, Ressom HW (2016). Metabolomic data deconvolution using probabilistic purification models. Oral Presentation in the Proceedings of the 2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), Shenzhen, China, December 15-18, 2016. (Awarded the Best Student Paper, 1/361)
Wang M, Tsai TH, Di Poto C, Ferrarini A, Yu G, Ressom HW (2016). Topic model-based mass spectrometric data analysis in cancer biomarker discovery studies. BMC Genomics, 17(Suppl 4):545.
Wang M, Yu G, Ressom HW (2016). Integrative analysis of proteomic, glycomic, and metabolomic data for biomarker discovery. IEEE J Biomed Health Inform, 20(5), 1225-1231. PMID: 27249841
Ressom HW, Di Poto C, Ferrarini A, Hu Y, Nezami Ranjbar MR, Song E, Varghese RS, Wang M, Zhou S, Zhu R, Zuo Y, Tadesse MG, Mechref Y (2016). Multi-omic approaches for characterization of hepatocellular carcinoma. Oral Presentation in the Proceedings of the 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Orlando, Florida, August 16-20, 2016.
Varghese RS, Di Poto C, Tu C, Nezami Ranjbar MR, Luo Y, Choi J, Tadesse MG, Ressom HW (2016). Assessment of GC-MS in detecting changes in the levels of metabolites using a spike-in experiment in human plasma. Accepted for Publication in Metabolomics: Open Access.
Zuo Y, Cui Y, Di Poto C, Varghese RS, Yu G, Li R, and Ressom HW (2016). INDEED: Integrated differential expression and differential network analysis of omic data for biomarker discovery. METHODS. 2016 Dec 1;111:12-20. doi: 10.1016/j.ymeth.2016.08.015. PMID: 27592383
Zuo Y, Cui Y, Yu G, Li R, and Ressom HW (2016). Integrating prior biological knowledge for network-based differential gene expression analysis using weighted graphical LASSO. BMC Bioinformatics. 2017 Feb 10;18(1):99. PMID: 28187708
Tsai TH, Wang M, Ressom HW (2016). Preprocessing and Analysis of LC-MS-Based Proteomic Data. Methods Mol Biol. 2016;1362:63-76. doi: 10.1007/978-1-4939-3106-4_3. PMID: 26519169, PMCID: PMC4838194
Zhao Y, Tsai TH, Di Poto C, Pannell LK, Tadesse MG, and Ressom HW (2016). Variability assessment of label-free LC-MS experiments for difference detection. In: Statistical Analysis of Proteomics, Metabolomics, and Lipidomics Data Using Mass Spectrometry. Eds. Datta S and Mertens BJA: Springer, 2016: 157-176
Varghese RS, Zuo Y, Zhao Y, Zhang YW, Jablonski SA, Pierobon M, Petricoin E, Ressom HW, Weiner LM (2016). Network-based analysis of reverse phase protein array data. Proceedings of the 2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), Shenzhen, China, December 15-18, 2016.
Year 2015
Ferrarini A, Di Poto C, Varghese RS, Nezami Ranjbar MR, Alonso DE, Binkley J, Ressom HW (2015). A multi-platform approach for metabolomic analysis of human liver tissues. Chromatography Today. August/September 2015.
Korba B, Shetty K, Medvedev A, Viswanathan P, Varghese RS, Zhou B, Roy R, Makambi K, Ressom HW, Loffredo C (2015). Hepatitis C virus genotype 1a core gene nucleotide patterns associated with hepatocellular carcinoma risk. Journal of General Virology. [Epub ahead of print] PMID: 26296571
Zhang YW, Nasto RE, Varghese R, Jablonski SA, Serebriiskii IG, Surana R, Calvert VS, Bebu I, Murray J, Jin L, Johnson M, Riggins R, Ressom HW, Petricoin E, Clarke R, Golemis EA, Weiner LM (2015). Acquisition of estrogen independence induces TOB1-related mechanisms supporting breast cancer cell proliferation. Oncogene. [Epub ahead of print] PMID: 26165839
Enquobahrie DA, Denis M, Tadesse MG, Gelaye B, Ressom HW, Williams MA (2015). Maternal early pregnancy serum metabolites and risk of gestational diabetes mellitus. J Clin Endocrinol Metab.
Wang M, Tsai TH, Yu G, Ressom HW (2015). Purification of LC/GC-MS based Biomolecular Expression Profiles Using a Topic Model. To appear in the Proceedings of the 2015 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), Washington D.C., USA, November 9-12, 2015.
Zuo Y, Yu G, and Ressom HW (2015). Integrating prior biological knowledge and graphical LASSO for network inference. To appear in the Proceedings of the 6th Workshop on Integrative Data Analysis in System Biology (IDASB), Washington DC, November 9-12, 2015.
Tsai TH, Wang M, Ressom HW (2015). Preprocessing and Analysis of LC-MS-Based Proteomic Data. Statistical Analysis in Proteomics (Methods in Molecular Biology), Editor: Klaus Jung, 1st Edition. ISBN-13: 978-1493931057.
Nezami Ranjbar MR, Di Poto C, Wang Y, Ressom HW (2015). SIMAT: GC-SIM-MS data analysis tool. BMC Bioinformatics 2015, 16:259. PMID: 26283310
Nezami Ranjbar MR, Luo Y, Di Poto C, Varghese RS, Ferrarini A, Zhang C, Sarhan NI, Soliman H, Tadesse MG, Ziada DH, Roy R, Ressom HW (2015). GC-MS based plasma metabolomics for identification of candidate biomarkers for hepatocellular carcinoma in Egyptian cohort. PLoS One 10(6):e0127299. PMID: 26030804
Wang M, Yu G, Ressom HW (2015). Integrative analysis of LC-MS based glycomic and proteomic data. To appear in the Proceedings of the 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Milano, Italy, August 25-29, 2015.
Tsai TH, Song E, Zhu R, Di Poto C, Wang M, Luo Y, Varghese RS, Tadesse MG, Ziada DH, Desai CS, Shetty K, Mechref Y, Ressom HW (2015). LC-MS/MS based Serum Proteomics for Identification of Candidate Biomarkers for Hepatocellular Carcinoma. Proteomics. 15(13), 2369-2381. PMID: 25778709
Wang J, Zuo Y, Man Y-G., Avital I, Stojadinovic A, Liu M, Yang X, Varghese RS, Tadesse MG, Ressom HW (2015). Pathway and network approaches for identification of cancer signature markers from omics data. Journal of Cancer 6(1): 54-65. PMID: 25553089
Nezami Ranjbar MR, Tadesse MG, Wang Y, Ressom HW (2015). Bayesian normalization model for Label-free quantitative analysis by LC-MS. IEEE/ACM Trans Comput Biol Bioinform. 12(4), 914-927. DOI 10.1109/TCBB.2014.2377723.
Year 2014
Zuo Y, Yu G, Zhang C, Ressom HW (2014). A new approach for multi-omic data integration. Proceedings of the 2014 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), Belfast, UK, November 2014, pp. 214-217. DOI: 10.1109/BIBM.2014.6999157
Tsai TH, Wang M, Di Poto C, Hu Y, Zhou S, Zhao Y, Varghese RS, Luo Y, Tadesse MG, Ziada DH, Desai CS, Shetty K, Mechref Y, Ressom HW (2014). LC-MS Profiling of N-Glycans Derived from Human Serum Samples for Biomarker Discovery in Hepatocellular Carcinoma. J Proteome Res. PMID: 25077556
Zuo, Y, Yu, G, Tadesse, MG, Ressom, HW (2014). Biological network inference using low order partial correlation. Methods. PMID: 25003577
Wang, J, Zuo, Y, Liu, L, Man, Y, Tadesse, MG, Ressom, HW (2014). Identification of Functional Modules by Integration of Multiple Data Sources Using a Bayesian Network Classifier. Circulation: Cardiovascular Genetics,7(2), 206-217. PMID: 24736851
Xiao JF, Zhao Y, Varghese RS, Zhou B, Di Poto C, Zhang L, Tadesse MG, Ziada DH, Shetty K, Ressom HW (2014). Evaluation of metabolite biomarkers for hepatocellular carcinoma through stratified analysis by gender, race and alcoholic cirrhosis. Cancer Epidemiol Biomarkers Prev. 23(1):64-72. PMID: 24186894
Year 2013
Tsai TH, Tadesse MG, Di Poto C, Pannell LK, Mechref Y, Wang Y, Ressom HW (2013). Multi-profile Bayesian alignment model for LC-MS data analysis with integration of internal standards. Bioinformatics 29(21):2774-80. PMID: 24013927
Zhang Z, Xuan J, Clarke R, Ressom HW (2013). Module-based breast cancer classification. Int J Data Min Bioinform. 7(3):284-302. PMID: 23819260
Nezami Ranjbar MR, Zhao Y, Tadesse MG, Wang Y, Ressom HW (2013). Gaussian process regression model for normalization of LC-MS data using scan-level information. Proteome Science 2013, 11(Suppl 1):S13.
Tsai TH, Tadesse MG, Wang Y, Ressom HW (2013). Profile-based LC-MS data alignment--a Bayesian approach. IEEE/ACM Trans Comput Biol Bioinform. 10(2):494-503. PMID: 23929872
MacArthur L, Ressom H, Shah S, Federoff HJ (2013). Network modeling to identify new mechanisms and therapeutic targets for Parkinson's disease. Expert Rev Neurother. 13(6):685-93. PMID: 23739005
Cheema AK, Varghese RS, Timofeeva O, Zhang L, Kirilyuk A, Zandkarimi F, Kaur P, Ressom HW, Jung M, Dritschilo A. (2013) Functional proteomics analysis to study ATM dependent signaling in response to ionizing radiation. Radiat Res. 179(6):674-83. PMID: 23642045
Zhou B, Xiao JF, Ressom HW. Prioritization of putative metabolite identifications in LC-MS/MS experiments using a computational pipeline. Proteomics. 2013 Jan;13(2):248-60. PMID: 23307777
Wu FX, Ressom H, Dunn MJ. Focus on bioinformatics in proteomics. Proteomics. 2013 Jan;13(2):219-20. PMID: 23341066
Hsu PC, Zhou B, Zhao Y, Ressom HW, Cheema AK, Pickworth W, Shields PG. Feasibility of Identifying the Tobacco-related Global Metabolome in Blood by UPLC-QTOF-MS. J Proteome Res. 2013 Feb 1;12(2):679-91.PMID: 23240883
Zuo Y, Yu G, Tadesse MG, Ressom HW (2013). "Reconstructing biological networks using low order partial correlation", Proceedings of the 2013 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), Shanghai, China, December 2013, pp. 171-175.
Wang M, Yu G, Mechref Y, Ressom HW (2013). "GPA: an algorithm for LC/MS based glycan profile annotation", Proceedings of the 2013 IEEE International Conference on Bioinformatics and Biomedicine Workshop (BIBMW), Shanghai, China, December 2013, pp. 16-22.
Year 2012
Xiao JF, Varghese RS, Zhou B, Nezami Ranjbar MR; Zhao Y, Tsai T-H,Di Poto C, Wang J, Goerlitz D, Luo Y, Cheema A, Sarhan N, Soliman H,Tadesse MG, Ziada DH, Ressom HW (2012). LC-MS based serum metabo-lomics for identification of hepatocellular carcinoma biomarkers in Egyptian cohort. J Proteome Res. 11(12):5914-23. PMID:23078175
Kaur P, Rizk NM, Ibrahim S, Younes N, Uppal A, Dennis K, Karve T,Blakeslee K, Kwagyan J, Zirie M, Ressom HW, Cheema AK (2012). iTRAQ-based quantitative protein expression profiling and MRM verification of markers in Type 2 diabetes. J Proteome Res. 11(11):5527-39. PMID: 23050762
Nezami Ranjbar MR, Zhao Y, Tadesse MG, Wang Y, Ressom HW (2012). Evaluation of normalization methods for analysis of LC-MS data. Proceedings of the 2012 IEEE International Conference on Bioinformatics and Biomedicine Workshop (BIBMW), Philadelphia, PA, October 2012, pp. 610-617.
Zhao Y, Tsai T-H, Di Poto C, Pannell L, Tadesse MG, Ressom HW (2012). Variability assessment of LC-MS experiments and its application to experimental design and difference detection. Proceedings of the 2012 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS), Washington, DC, December 2012, 195-198.
Nezami Ranjbar MR, Tadesse MG, Wang Y, Ressom HW (2012). Normalization of LC-MS data using Gaussian process. Proceedings of the 2012 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS), Washington, DC, December 2012, pp. 1870190.
Wang J, Yuan H, Tadesse MG, Ressom HW (2012). Integration of multiple data sources for identifying functional modules using Bayesian network. Proceedings of the 2012 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS), Washington DC, December 2012, pp. 13-17.
Ressom HW, Xiao JF, Tuli L, Varghese RS, Zhou B, Tsai T-H, Nezami Ranjbar MR, Zhao Y, Wang J, Di Poto C, Cheema AK, Tadesse MG, Goldman R, Shetty K (2012). Utilization of metabolomics to identify serum biomarkers for hepatocellular carcinoma in patients with liver cirrhosis. Anal Chim Acta. 2012 Sep 19;743C:90-100. PMID: 22882828
Zhou B, Wang J, Ressom HW (2012). MetaboSearch: Tool for mass-based metabolite identification using multiple databases. PLoS One 7(6): e40096. doi:10.1371/journal.pone.0040096. PMID: 22768229
Tuli L, Tsai T-H, Varghese R, Xiao JF, Cheema A, and Ressom HW (2012). Using a spike-in experiment to evaluate analysis of LC-MS data. Proteome Science. Proteome Science 10(1):13.
Zhang Z, Xuan J, Clarke R, Ressom HW (2012). Module-based breast cancer classification. Int J Data Min Bioinform. 2013;7(3):284-302. PMID: 23819260
Varghese RS, Zhou B, Nezami Ranjbar MR, Zhao Y, Ressom HW (2012). Ion annotation-assisted analysis of LC-MS based metabolomic experiment. Proteome Sci. 2012 Jun 21;10 Suppl 1:S8.
Scholz SW, Mhyre T, Ressom H, Shah S, Federoff HJ (2012). Genomics and bioinformatics of Parkinson's disease. Cold Spring Harb Perspect Med. 2012 Jul;2(7):a009449.
Wang J, Zhang y, Marian C, Ressom HW (2012). Identification of aberrant pathways and network activities from high-throughput data. Briefings in Bioinformatics. 13(4):406-19. PMID: 22287794
Xiao JF, Zhou B, Ressom HW (2012). Metabolite identification and quantitation in LC-MS/MS-based metabolomics. Trends Analyt Chem 32:1-14.
Zhou B, Xiao JF, Tuli L, Ressom HW (2012). LC-MS-based metabolomics. LC-MS-based metabolomics. Mol. BioSyst. 8(2) 470-481.
Kaur P, Sheikh K, Kirilyuk A, Kirilyuk K, Kallakury B, Ressom HW, Cheema A (2012). Metabolomic profiling for biomarker discovery in pancreatic cancer. International Journal of Mass Spectrometry 310: 44-51.
Kamalru AA, Baharum SN, Ressom HW, Noor NM (2012). GC-MS analysis and PLS-DA validation of the trimethyl silyl-derivatization techniques. American Journal of Applied Sciences. American Journal of Applied Sciences 9 (7): 1124-1136, 2012.
Patacsil D, Tran AT, Cho YS, Suy S, Saenz F, Malyukova I, Ressom H, Collins SP, Clarke R, Kumar D (2012). Gamma-tocotrienol induced apoptosis is associated with unfolded protein response in human breast cancer cells. J Nutr Biochem. 2012 Jan;23(1):93-100. Epub 2011 Mar 22.
Year 2011
Befekadu GK, Tadesse MG, Tsai T-H, Ressom HW (2011). Probabilistic mixture regression models for alignment of LC-MS data. IEEE/ACM Trans Comput Biol Bioinform 8(5):1417-24.
Tang Z, Zhang L, Cheema A, Ressom HW (2011). A new method for alignment of LC-MALDI-TOF data. Proteome Science 9 (Suppl 1):S1.
Cheema AK, Timofeeva O, Varghese R, Dimtchev A, Shiekh K, Shulaev V, Suy S, Collins S, Ressom H, Jung M, Dritschilo A* (2011). Integrated analysis of ATM mediated gene and protein expression impacting cellular metabolism. J Proteome Res. 2011 May 6;10(5):2651-7. Epub 2011 Mar 7.
Ochs MF, Karchin R, Ressom H, Gentleman R (2011). Identification of aberrant pathway and network activity from high-througput data - workshop introduction. Pac Symp Biocomput. 2011:364-8.
Tsai T-H, Tadesse MG, Wang Y, and Ressom HW (2011). Bayesian alignment model for LC-MS data. Proceedings of the IEEE International Conference on Bioinformatics & Biomedicine, Atlanta, GA, November 12-15, 2011, pp. 261-264.
Zhou B, Xiao JF, Ressom HW (2011). A computational pipeline for LC-MS/MS based metabolite identification. Proceedings of the IEEE International Conference on Bioinformatics & Biomedicine, Atlanta, GA, November 12-15, 2011, pp. 247-251.
Varghese RS, Zhou B, Ressom HW (2011). Meta-analysis of LC-MS based metabolomic experiments. Proceedings of the Third International Workshop on Data Mining for Biomarker Discovery (DMBD 2011), Atlanta, GA, November 12-15, 2011, pp. 157-164.
Patacsil D, Tran AT, Cho YS, Suy S, Saenz F, Malyukova I, Ressom H, Collins SP, Clarke R, Kumar D (2011). Gamma-tocotrienol induced apoptosis is associated with unfolded protein response in human breast cancer cells. J Nutr Biochem. 2011 Mar 21. [Epub ahead of print] PMID:21429729
Cheema AK, Timofeeva O, Varghese R, Dimtchev A, Shiekh K, Shulaev V, Suy S, Collins S, Ressom H, Jung M, Dritschilo A (2011). Integrated analysis of ATM mediated gene and protein expression impacting cellular metabolism. J Proteome Res. 2011 Mar 7. [Epub ahead of print]
Ochs MF, Karchin R, Ressom H, Gentleman R (2011). Identification of aberrant pathway and network activity from high-througput data - workshop introduction. Pac Symp Biocomput. 2011:364-8.
Varghese RS and Ressom HW (2011). LC-MS data analysis for differential protein expression detection. Methods Mol Biol. 2011;694:139-50.
Year 2010
Varghese RS, Cheema A, Cheema P, Bourbeau M, Tuli L, Zhou B, Jung M, Dritschilo A, Ressom HW (2010). Analysis of LC-MS data for characterizing the metabolic changes in response to radiation. J Proteome Res. 9(5):2786-93.
Zhang Y, Xuan J, de los Reyes BG, Clarke R, Ressom HW (2010). Reconstruction of gene regulatory modules in cancer cell cycle by multi-source data integration. PLoS One 5(4):e10268.
Tang Z, Varghese RS, Bekesova S, Loffredo CA, Abdel-Hamid M, Kyselova Z, Mechref Y, Novotny M, Goldman R, Ressom HW (2010). Identification of N-glycan serum markers associated with hepatocellular carcinoma from mass spectrometry data. J Proteome Res. 9(1):104-12.
Prahalad P, Dakshanamurthy S, Ressom H, Byers SW (2010). Retinoic acid mediates regulation of network formation by COUP-TFII and VE-cadherin expression by TGFbeta receptor kinase in breast cancer cells. PLoS One 5(4):e1002.
Befekadu GK, Tadesse MG, Tsai T-H, Ressom HW. Probabilistic mixture regression models for alignment of LC-MS data. IEEE/ACM Trans Comput Biol Bioinform. 2010 Sep 8. [Epub ahead of print] PMID: 20837998
Zhou B, Cheema A, Ressom HW (2010). SVM-based spectral matching for metabolite identification. Proceedings of the 32nd Annual Conference of the IEEE Engineering in Medicine and Biology Society, Buenos Aires, Argentina, August 31 - September 4, 2010, pp. 756-759.
Tang Z, Zhang L, Cheema A, Ressom HW (2010). A new method for alignment of LC-MALDI-TOF data. Proceedings of the IEEE International Conference on Bioinformatics & Biomedicine, December 18-21, Hong Kong. 2010, pp.346-351.
Zhang Y, Xuan J, Clarke R, Ressom HW (2010). Module-based biomarker discovery in breast cancer. Proceedings of the IEEE International Conference on Bioinformatics & Biomedicine, December 18-21, Hong Kong. 2010, pp.352-356.
Tuli L, Tsai T-H, Varghese R, Cheema A, and Ressom HW (2010). Using a spike-in experiment to evaluate analysis of LC-MS data. Proceedings of the IEEE International Workshop on Computational Proteomics, December 18-21, Hong Kong. 2010, pp.67-72.
Kaur P, Sheikh K, Kirilyuk A, Kirilyuk K, Kallakury B, Ressom HW, Cheema A (2010). Metabolomic profiling for biomarker discovery in pancreatic cancer. Proceedings of the IEEE International Conference on Bioinformatics & Biomedicine, December 18-21, Hong Kong. 2010. pp. 505-509.